AWS Lake Formation now supports accessing Glue Data Catalog databases and tables across Regions. Previously, in order to access the Glue Data Catalog databases and tables from a different Region, you had to replicate the catalog items and/or underlying data from the source Region to the local Region. Now, with the cross-Region support in Lake Formation, you can access the Glue catalog databases and tables from any Region that Lake Formation is available. Each feature of Lake Formation, such as LF-Tags based access control, fine grained access permissions at the row and column level, data filters, and sharing to direct IAM principals across accounts are available with cross-Region table access. Lastly, you can also run queries that join tables between local Region tables and cross-Region tables.
Source:: Amazon AWS